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We can detect when the cigarette is being lit, when the person holds it to his or her mouth and takes a puff, how much smoke was inhaled, how much time between puffs and how long the cigarette has been in the mouth. The topography of smoking All these details are called smoking topography, which is important because it allows scientists to measure and assess toxic carbon monoxide exposure among smokers and understand more deeply the relationship between chemical exposure and tobacco-related diseases including cancer, heart disease, stroke, lung disease, diabetes, COPD, emphysema and chronic bronchitis